Glutathione Pathways Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells Cell Death & Disease Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione DepletionInduced Activation of Dimersomes for Potentiating the Ferroptosis and Immunotherapy of Cold Tumor Zhou 2022 Angewandte Chemie International Edition Wiley Online Library Application of glutathione depletion in cancer therapy: Enhanced ROS based therapy, ferroptosis, and chemotherapy ScienceDirect Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification