Pigmentation Document Gale OneFile: Health and Medicine Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor a Melanotic macule at the wetdry line of the lower lip. b Melanotic Download Scientific Diagram Clinical Challenge: Dark Lesion on Lower Lip MPR Pathology Outlines Melanotic macule Spotty lips. These are labial melanotic macules, kinda like freckles on the lips. They are mostly due to age and sun exposure, but sometimes they run in families and are associated with