Methylcobalamin 10,000mcg injectable, 10mL (lyophilized) Defy Medical Safe IM Injection Site Intramuscular injection should always be given in the **upper outer quadrant of the gluteal region** to prevent sciatic nerve injury. Key nursing points: Upper outer quadrant = How to self inject intramuscular vitamin B12 Overview Guy's and St Thomas' NHS Foundation Trust INTRAMUSCULAR INJECTION SITES Intramuscular (IM) injections are given directly into the muscle, where the medication is absorbed more quickly than subcutaneous injections. There are several Nwokeiwu Valentine How to give yourself an injection? A guide to subcutaneous and intramuscular injections. Medbasic Best Vitamin B12 Injection Sites: Where to Inject B12 PA Relief