Despite the name "melanosis," the pigment isn't melanin. The Pigment: It is actually lipofuscin, a "wear and tear" pigment. The Process: Anthraquinone laxatives cause apoptosis (cell death) of the colonic epithelial cells. Amelanotic Melanoma Pictures Melanotic Schwannoma Basicmedical Key Melanocytic Naevus Ballarat Skin Cancer Centre New Insights into Melanocytes Beyond Conventional Recognition Encyclopedia MDPI Labial melanotic macule