About Your Peripherally Inserted Central Catheter (PICC) Memorial Sloan Kettering Cancer Center When can I remove the dressing from my picc line insertion? PICC Line Together by St. Jude How Often Do You Change A Picc Line Dressing This is my weekly PICC line dressing change. I am not a licensed RN and these are purely my experiences in the hospital. If youd like to follow my story, PleaSE! LiKE! fOllOw! and ShArE! at Procedure: Arterial and Central Venous Assessment, Maintenance and Dressing Change LHSC