From melanocytes to melanomas Nature Reviews Cancer Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) La Bouche Parfaite Feline Iris Hyperpigmentation MSPCA Angell ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Melanoma Pictures: Skin Changes and What to Look For Oral Melanotic Macule: Symptoms and Treatment Skinsight