AngIV Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP PS1 Mouse via the PI3K AKT Signaling Pathway DIHEXA Neuronal hyperexcitability in Alzheimer's disease: what are the drivers behind this aberrant phenotype? Translational Psychiatry Single cell insights into an Alzheimer's disease drug target 10x Genomics Alzheimer's Disease Puzzle: Delving into Pathogenesis Hypotheses Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted