G6PD Deficiency causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( HMP Pathway Simplified: NADPH Role & G6PD Deficiency Explained G6PD Deficiency and G6PD Activity Testing Mindray Figure 2 from Impact of glucose 6 phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Semantic Scholar File:Glutathion metabolism DE state in G6PD deficiency.png Wikimedia Commons Glutathione Reductase (GR) The Scout for Liver Health