Dihexa: The Powerful Key To Enhancing Cognitive Performance And Optimizing Brain Health Dihexa rescued the cognitive ability of APP PS1 mice. (A) Dihexa Download Scientific Diagram Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted EllieMD Dihexa Surprise: HDAC Goes Down, Not Up, in Alzheimer's Disease ALZFORUM Alzheimer's disease may damage the brain in two phases National Institutes of Health (NIH)