Conjunctival Nevus: Symptoms, Causes and Treatment Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Differentiating between early melanomas and melanocytic nevi: A state of the art review ScienceDirect Oral Melanotic Macule: Symptoms and Treatment Skinsight Oral melanotic macules are harmless but can be removed easily with laser treatment! Quick, safe, and effective. Say hello to even toned lips! #laser #candela #pico #lips #face #makeup #spa Melanosis coli: Symptoms, causes, treatment, and more